Differs alveolus-arterial of oxygen and mortality for pneumonia COVID-19
Keywords:
COVID-19, coronavirus infections, risk factorsAbstract
Objective: To determine the relationship between the alveolus-arterial difference of oxygen and the mortality in patient with pneumonia COVID-19 discharged of the of intensive cares unit at the Hospital General Docente Dr. Agostinho Neto of Guantánamo during 2020-2021.
Methods: Was carried out an explanatory, retrospective and traverse study of patient discharged of the intensive care’s unit (n = 168) with diagnostic pneumonia COVID-19 and abnormality of the alveolus-arterial difference of oxygen. They were studied to the expenditure, age, sex, comorbidities, treatment with ventilation mechanics, neutrophil to lymphocyte ratio, oxygenation indicators, and presentation of acute respiratory distress syndrome. Chi-square was used to identify the relationship between the variables with the probability of died discharge. The odds ratio (OR) was calculated for each studied variable.
Results: The factors more associated to the probability of dying were the presentation of acute respiratory distress syndrome (OR = 24.1 [IC 95% 11.4-32.4] p = 0.000), treatment with invasive ventilation mechanics (OR = 16.7 [IC 95 % 6,0-44.5] p = 0.000) and neutrophil to lymphocyte ratio bigger than 3.5 at the 48 hours of the entrance (OR = 11.5 [IC 95% 4.3-30.8] p = 0.000).
Conclusions: The determination of the value of the alveolus-arterial difference of oxygen was a factor predictor of mortality in patient with pneumonia COVID-19 discharged of the intensive cares unit at the Dr. Agostinho Neto Hospital.
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References
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