Encephalitis due to antibodies against N-Methyl-D-Aspartate receptors
Keywords:
autoimmunity, encephalitis, N-Methyl-D-Aspartate receptorsAbstract
Introduction: Encephalitis due to anti-N-Methyl-D-Aspartate receptor antibodies is a predominant disease in young patients.
Objective: To describe the clinical course and treatment of a patient diagnosed with encephalitis due to anti-N-Methyl-D-Aspartate receptor antibodies.
Case report: This is the case of a 23 year-old female patient, operated on for atrial septal defect fifteen years ago. She was brought to the health center due to seizures, psychomotor excitement, auditory hallucinations and long-standing behavioral changes, with worsening in recent weeks. For diagnostic confirmation, the clinical criteria of probability and definitive (a posteriori) were met. The evolution was favorable by using the prescribed therapy.
Conclusions: Encephalitis due to anti-N-Methyl-D-Aspartate receptor antibodies is part of the autoimmune encephalitides and it is currently treatable. His clinic, characterized by neuropsychiatric symptoms, seizures and abnormal movements, should lead to suspect the possibility of this neurological disease. The clinical and analytical characteristics of the reported case agreed with the established diagnostic criteria. The prognosis is usually favorable, due to adequate response to immunosuppressive therapy, which occurred in the case reported.
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