Ácido tranexámico para hemorragia intracerebral primaria hiperaguda

Luis Rafael Moscote-Salazar, Ezequiel Ballestas-García, Hugo Rafael Corrales Santander, Huber S. Padilla-Zambrano

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Referencias

Sprigg N, Flaherty K, Appleton JP, Salman RAS, Bereczki D, Beridze M, et al. Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial. Lancet. 2018;391(10135):2107-15.

Sprigg N, Robson K, Bath P, Dineen R, Roberts I, Robinson T, et al. Intravenous tranexamic acid for hyperacute primary intracerebral hemorrhage: Protocol for a randomized, placebo-controlled trial. Int J Stroke. 2016;11(6):683-94.

Flaherty K, Bath PM, Dineen R, Law Z, Scutt P, Pocock S, et al. Statistical analysis plan for the “Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage” (TICH-2) trial. Trials. 2017;18(1):17-9.

Ovesen C, Jakobsen JC, Gluud C, Steiner T, Law Z, Flaherty K, et al. Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre ‑ specified sub ‑ study of the TICH ‑ 2 trial. BMC Res Notes. 2018;11(1):379. Doi: 10.1186/s13104-018-3481-8

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Dineen RA, Pszczolkowski S, Flaherty K, Law ZK, Morgan PS, Roberts I, et al. Does tranexamic acid lead to changes in MRI measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? Protocol for a MRI substudy nested within the double-blind randomised controlled TICH-2 trial. BMJ Open. 2018;8(2):e019930.

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